Landscapes of Heathrow : the aircraft landing gear compartment and the politics of global transfer

This paper, an output of an art research project, explores the agency of the aircraft landing gear compartment in global transfer. Through the prism of historical events involving aircraft preparing to land at London Heathrow, it reflects on the part played by the compartment in ecological and humanitarian struggle. Its theoretical frameworks include John Ruskin’s writing on geology, new materialism, and the planetary garden. These are brought into proximity with methodologies and collaborations developed through practice-based elements of the research, such as architectural modelling, geoforensic science and exhibition making. It incorporates an account of the process of reconstructing a compartment, as well as extracts from a microstratigraphic survey commissioned as part of the project. It examines the landing gear compartment’s capacity as a vessel in which dust, seeds, insects, pollen and even people are transported around the globe. It explores, too, its role as expository instrument, as far as it makes available for inspection the politics inscribed into its formal, spatial and temporal configuration. The paper argues that the wheel bay gives shape to a set of otherwise intangible aeromobilities, knowledge of which is integral to a nuanced understanding of the political geography of London Heathrow

Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

To understand neurological complications of COVID-19 better both acutely and for recovery, we measured markers of brain injury, inflammatory mediators, and autoantibodies in 203 hospitalised participants; 111 with acute sera (1–11 days post-admission) and 92 convalescent sera (56 with COVID-19-associated neurological diagnoses). Here we show that compared to 60 uninfected controls, tTau, GFAP, NfL, and UCH-L1 are increased with COVID-19 infection at acute timepoints and NfL and GFAP are significantly higher in participants with neurological complications. Inflammatory mediators (IL-6, IL-12p40, HGF, M-CSF, CCL2, and IL-1RA) are associated with both altered consciousness and markers of brain injury. Autoantibodies are more common in COVID-19 than controls and some (including against MYL7, UCH-L1, and GRIN3B) are more frequent with altered consciousness. Additionally, convalescent participants with neurological complications show elevated GFAP and NfL, unrelated to attenuated systemic inflammatory mediators and to autoantibody responses. Overall, neurological complications of COVID-19 are associated with evidence of neuroglial injury in both acute and late disease and these correlate with dysregulated innate and adaptive immune responses acutely

Evaluation of digital libraries

Περιέχει το πλήρες κείμενοDigital libraries (DLs) are new and innovative information systems, under constant development and change, and therefore evaluation is of critical importance to ensure not only their correct evolution but also their acceptance by the user and application communities. The Evaluation activity of the DELOS Network of Excellence has performed a large-scale survey of current DL evaluation activities. This study has resulted in a description of the state of the art in the field, which is presented in this paper. The paper also proposes a new framework for the evaluation of DLs, as well as for recording, describing and analyzing the related research field. The framework includes a methodology for the classification of current evaluation procedures. The objective is to provide a set of flexible and adaptable guidelines for DL evaluation